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MSN-125

SKU T16155-25 mg Category Small Compound Brand: TargetMol

Price range: 2,432 CAD through 4,000 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) (IC50: 4 μM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16155

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C36H38BrN3O6

References

– Niu X, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chem Biol. 2017 Apr 20;24(4):493-506.e5.

CAS Number

– 1592908-16-1

Molecular Weight

– C36H38BrN3O6

SMILES

– COCCOCOc1ccc2[C@@H]([C@@H](CN)Oc2c1)N(Cc1ccc(Br)cc1)C(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1

Target

– Others

Pathway

– PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.