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ML364

SKU T3555-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 106 CAD through 1,576 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3555

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H18F3N3O3S2

Citations

– 1. Zhang F, Zhao Y, Sun Y. USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates. Journal of Biological Chemistry. 2021, 297(4)

References

– Davis MI,et al. Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models. J Biol Chem. 2016 Nov 18;291(47):24628-24640. Epub 2016 Sep 28.

CAS Number

– 1991986-30-1

Molecular Weight

– C24H18F3N3O3S2

Compound Purity

– 0.9992

SMILES

– Cc1ccc(cc1)S(=O)(=O)Nc1cc(ccc1C(=O)Nc1nc(cs1)-c1ccccc1)C(F)(F)F

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.