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ML141

SKU T2463-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 53 CAD through 2,112 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2463

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H21N3O3S

Citations

– 1. Lv J, Zeng J, Guo F, et al. Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury. Respiratory Research. 2018, 19(1): 1-11 2. Wang C, Hu R, Wang T, et al.A bivalent β-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605. 3. Wang K, Ge Y, Yang Y, et al.Vascular endothelial cellular mechanics under hyperglycemia and its role in tissue regeneration.Regenerative Biomaterials.2024: rbae004. 4. Li J, Lv L, Gao Y, et al.Tetraspanin CD81 serves as a functional entry factor for porcine circovirus type 2 infection.Journal of Virology.2024: e01408-24.

References

– Surviladze Z, et al. National Center for Biotechnology Information (US); 2010.

CAS Number

– 71203-35-5

Molecular Weight

– C22H21N3O3S

Compound Purity

– 0.9977

SMILES

– COC1=CC=C(C=C1)C1CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C1=CC=CC=C1

Pathway

– GPCR/G Protein|||Apoptosis|||MAPK|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.