Download Files:

Mertansine

SKU T1992-1 mg Category PROTAC Brand: TargetMol

Price range: 48 CAD through 525 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1992

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H48ClN3O10S

Citations

– 1. Wang Y Q, Ji M Y, Wang C. Endoplasmic reticulum-targeted glutathione and pH dual responsive vitamin lipid nanovesicles for tocopheryl DM1 delivery and cancer therapy. International Journal of Pharmaceutics. 2020: 119331.

References

– Whiteman KR, et al. MAbs. 2014 Mar-Apr;6(2): 556-66.

CAS Number

– 139504-50-0

Molecular Weight

– C35H48ClN3O10S

Compound Purity

– 0.9976

SMILES

– CO[C@@H]1C=C/C=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2

Target

– Others

Pathway

– Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.