LY 222306

SKU T11921-25 mg Category Small Compound Brand: TargetMol

Price range: 2,672 CAD through 4,480 CAD

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Product Description

– LY 222306, a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor, has a Ki of 0.77 nM.

Web ID

– T11921

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H23N5O7

References

– Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.

CAS Number

– 154446-98-7

Molecular Weight

– C19H23N5O7

SMILES

– O=C1C2=C(NCC(CCC=3OC(C(N[C@@H](CCC(O)=O)C(O)=O)=O)=CC3)C2)NC(N)=N1

Target

– HDAC|||Apoptosis

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

LY 222306

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