Download Files:
Luteolin
Price range: 62 CAD through 347 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T1027
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H10O6
Citations
– 1. Tan X, Yang Y, Xu J, et al. Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage. Frontiers in Pharmacology. 2020, 10: 1551
2. Yang Y, Tan X, Xu J, et al. Luteolin alleviates neuroinflammation via downregulating the TLR4/TRAF6/NF-κB pathway after intracerebral hemorrhage. Biomedicine & Pharmacotherapy. 2020, 126: 110044
3. Zhang Y, Yu F, Hao J, et al. Study on the Effective Material Basis and Mechanism of Traditional Chinese Medicine Prescription (QJC) Against Stress Diarrhea in Mice. Frontiers in Veterinary Science. 2021, 8.
4. Ding X, Zheng L, Yang B, et al. Luteolin Attenuates Atherosclerosis Via Modulating Signal Transducer And Activator Of Transcription 3-Mediated Inflammatory Response. Drug Des Devel Ther. 2019, 13: 3899.
5. Hwang Y H, Jang S A, Kim T, et al. Anti-osteoporotic and Anti-adipogenic Effects of Rhus chinensis Nutgalls in Ovariectomized Mice Fed with a High-fat Diet. Planta Medica. 2019, 85(14/15): 1128-1135
6. Xiao Z, Xu H, Qu Z, et al. Active Ingredients of Reduning Injections Maintain High Potency against SARS-CoV-2 Variants. Chinese Journal of Integrative Medicine. 2022: 1-8.
7. Dong J, Xu O, Wang J, et al. Luteolin ameliorates inflammation and Th1/Th2 imbalance via regulating the TLR4/NF-κB pathway in allergic rhinitis rats. Immunopharmacology and Immunotoxicology. 2021 Jun;43(3):319-327. doi: 10.1080/08923973.2021.1905659. Epub 2021 Apr 26.
8. Jung M A, Song H K, Jo K, et al.Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.Biomedicine & Pharmacotherapy.2023, 161: 114482.
9. Zhu Y, Bao G, Zhu G, et al.Discovery and characterization of natural product luteolin as an effective inhibitor of human pyridoxal kinase.Bioorganic Chemistry.2023: 107057.
10. Yu S, Wu R, Si Y, et al.Alternative splicing of ALDOA confers tamoxifen resistance in breast cancer.Oncogene.2024: 1-13.
References
– Chen P, et al. Luteolin inhibits cell proliferation and induces cell apoptosis via down-regulation of mitochondrial membrane potential in esophageal carcinoma cells EC1 and KYSE450. Oncotarget. 2017 Apr 18;8(16):27471-27480.
CAS Number
– 491-70-3
Molecular Weight
– C15H10O6
Compound Purity
– 0.9811
SMILES
– O=C1C=2C(OC(=C1)C3=CC(O)=C(O)C=C3)=CC(O)=CC2O
Target
– Others
Pathway
– Apoptosis|||Metabolism|||Immunology/Inflammation|||Autophagy
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
Proudly representing
150+ years of combined research-supply heritage
