LT052

SKU T11887-1 mg Category Brand:

54 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– LT052 is a selective and efficient BET BD1 inhibitor with anti-inflammatory activity. It mediates the BRD4/NF-κB/NLRP3 inflammatory signaling pathway and can be used in gout arthritis research.

Web ID

– T11887

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H19N5O4S

References

– Jiang F, et al. Discovery of Benzo[cd]indol-2(1H)-ones and Pyrrolo[4,3,2-de]quinolin-2(1H)-ones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain with Potential High Efficiency against Acute Gouty Arthritis. J Med Chem. 2019 Dec 26;62(24):11080-11107.

CAS Number

– 2543545-44-2

Molecular Weight

– C22H19N5O4S

Compound Purity

– 0.9882

SMILES

– O=C1C2=CC(=NC3=C(C=CC(=C32)N1C)NS(=O)(=O)C=4C=CC=CC4OC)N5C=NC(=C5)C

Target

– ADC Linker

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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