LSN3074753

Name: LSN3074753 | DIMER Inhibitor — Buy Online | Immunomart
Brand: TargetMol
SKU: T89906-10 mg

SKU T89906-10 mg Category Small Compound Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– LSN3074753, a derivative of LY3009120, acts as a pan-RAF and Raf dimer inhibitor. This compound exhibits inhibitory activity against tumor cells driven by either BRAF monomers or RAF dimers, particularly in the activation of the MAPK pathway, including colorectal cancers with BRAF or KRAS mutations. When combined with Cetuximab, LSN3074753 demonstrates additive and synergistic effects in colorectal cancer PDX models, especially in those harboring KRAS or BRAF mutations.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T89906

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H30FN5O2

CAS Number

– 1455031-68-1

Molecular Weight

– C24H30FN5O2

SMILES

– CC=1C(=CC2=C(N1)C=C(NC)N=C2)C3=CC(NC(NC[C@H](C(C)(C)C)O)=O)=C(F)C=C3C

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.