LRP-6 Protein, Human, Recombinant (mFc)

SKU TMPK-00744-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 594 CAD through 2,384 CAD

Size

100 μg 500 μg

Clear

Products Details

Product Description

– Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer’s disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin. LRP-6 Protein, Human, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is O75581-1.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-00744

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Ren S, et al. LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1440-5. doi: 10.1073/pnas.1211179110. Epub 2013 Jan 9. Erratum in: Proc Natl Acad Sci U S A. 2016 Nov 14;: PMID: 23302695; PMCID: PMC3557093.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.