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Licochalcone D

SKU T4518-1 mg Category Natural Product Brand: TargetMol

Price range: 155 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4518

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H22O5

Citations

– 1. Lu X, Ji Q, Pan H, et al.IL-23p19 deficiency reduces M1 macrophage polarization and improves stress-induced cardiac remodeling by alleviating macrophage ferroptosis in mice.Biochemical Pharmacology.2024: 116072.

References

– Wang P, et al. Licochalcone C induces apoptosis via B-cell lymphoma 2 family proteins in T24 cells[J]. Molecular Medicine Reports, 2015, 12(5):7623.

CAS Number

– 144506-15-0

Molecular Weight

– C21H22O5

Compound Purity

– 0.999

SMILES

– COc1c(O)c(O)ccc1C=CC(=O)c1ccc(O)c(CC=C(C)C)c1

Pathway

– NF-κB|||MAPK

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.