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Lexatumumab
$300 – $1,250
Products Details
Product Description
– Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research[1].
Web ID
– HY-P99299
Storage Temperature
– Store at -80°C for 2 years
Shipping
– Dry Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– N/A
References
– [1]Belyanskaya LL, et al. Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin. Mol Cancer. 2007 Oct 22;6:66.|[2]Engesæter B, et al. Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma. PLoS One. 2012;7(9):e45492.
CAS Number
– 845816-02-6
Molecular Weight
– 143.6 (kDa)
Compound Purity
– 96.95
SMILES
– [Lexatumumab]
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– H2O
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
