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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induces apoptosis in A549 cells independently of cell cycle arrest, mediated by JNK and p38 MAPK signaling pathways. These pathways are activated due to oxidative DNA damage from increased ROS generation in MNQ-treated A549 cells.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T3008
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H8O3
Citations
– 1. Parat V, Onteniente B, Maruotti J. A high-throughput screening platform for pigment regulating agents using pluripotent stem cell derived melanocytes. Experimental Dermatology. 2020
2. Zhang H, Cai J, Li C, et al.Wogonin inhibits latent HIV-1 reactivation by downregulating histone crotonylation.Phytomedicine.2023: 154855.
References
– Ong J Y H , Yong P V C , Lim Y M , et al. 2-Methoxy-1,4-naphthoquinone (MNQ) induces apoptosis of A549 lung adenocarcinoma cells via oxidation-triggered JNK and p38 MAPK signaling pathways[J]. Life Sciences, 2015, 135:158-164.
CAS Number
– 2348-82-5
Molecular Weight
– C11H8O3
Compound Purity
– 0.9941
SMILES
– COC1=CC(=O)c2ccccc2C1=O
Pathway
– Apoptosis|||Microbiology/Virology
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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