CgoaEGayVBKECeHgAAAAAPpZwdU385- Immunomart

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L002

SKU T11807-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 907 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By blocking histone acetylation, p53 acetylation, and STAT3 activation, L002 shows potential in the treatment of hypertension‐induced cardiac hypertrophy and fibrogenesis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11807

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H15NO5S

References

– Rai R, et al. A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis. Epigenetics. 2017;12(11):1004-1013.

CAS Number

– 321695-57-2

Molecular Weight

– C15H15NO5S

Compound Purity

– 0.9859

SMILES

– COc1ccc(cc1)S(=O)(=O)ON=C1C=C(C)C(=O)C(C)=C1

Target

– Drug-Linker Conjugates for ADC

Pathway

– Chromatin/Epigenetic|||Stem Cells|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.