Kremen-1 Protein, Human, Recombinant (hFc)

SKU TMPK-01144-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 930 CAD through 3,728 CAD

Size

100 μg 500 μg

Clear

Products Details

Product Description

– KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-01144

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Cui Y, et al. Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRMProc Natl Acad Sci U S A. 2020 Aug 4;117(31):18711-18718. doi: 10.1073/pnas.2005341117. Epub 2020 Jul 20. PMID: 32690697; PMCID: PMC7414063.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.