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JQ-1 (carboxylic acid)

SKU T5443-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 102 CAD through 595 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T5443

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H17ClN4O2S

Citations

– 1. Zhao L, Zhu Y, Tao H, et al.Ailanthone ameliorates pulmonary fibrosis by suppressing JUN-dependent MEOX1 activation.Acta Pharmaceutica Sinica B.2024

References

– Rosner M , Hengstschl?Ger M . Targeting Epigenetic Readers in Cancer[J]. New England Journal of Medicine, 2012, 367(18):1764-1765.

CAS Number

– 202592-23-2

Molecular Weight

– C19H17ClN4O2S

Compound Purity

– 0.999

SMILES

– CC=1C2=C(N3C([C@H](CC(O)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C

Pathway

– Chromatin/Epigenetic

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.