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JNJ-55511118
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– JNJ-55511118 is a highly efficient and selective TARP γ8 negative allosteric modulator with anticonvulsant and neuroprotective activities. By reducing the peak current of AMPAR containing γ8, it can be used for research on chronic operant alcohol self-administration.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T25558
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H8ClF3N2O2
References
– Maher MP, Wu N, Ravula S, Ameriks MK, Savall BM, Liu C, Lord B, Wyatt RM, Matta JA, Dugovic C, Yun S, Ver Donck L, Steckler T, Wickenden AD, Carruthers NI, Lovenberg TW. Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8. J Pharmacol Exp Ther. 2016 May;357(2):394-414. doi: 10.1124/jpet.115.231712. Epub 2016 Mar 17. PubMed PMID: 26989142.
CAS Number
– 2036081-86-2
Molecular Weight
– C14H8ClF3N2O2
SMILES
– O=C1NC=2C=CC(=CC2N1)C=3C(Cl)=CC=CC3OC(F)(F)F
Pathway
– Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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