JAM-A Protein, Mouse, Recombinant (His)

SKU TMPK-00188-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 669 CAD through 2,672 CAD

Size

100 μg 500 μg

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Products Details

Product Description

– junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-00188

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Turaga SM, et al. JAM-A functions as a female microglial tumor suppressor in glioblastoma. Neuro Oncol. 2020 Nov 26;22(11):1591-160doi: 10.1093/neuonc/noaa148. PMID: 32592484; PMCID: PMC7690368.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.