JAK-IN-3

SKU T11704-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 216 CAD through 6,048 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11704

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H20N4O3

References

– Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

CAS Number

– 1400876-94-9

Molecular Weight

– C18H20N4O3

Compound Purity

– 0.9819

SMILES

– N([C@@H]([C@@H](C)O)CO)C=1C=2N(C=C(C2)C3=CC=CC=C3)N=CC1C(N)=O

Target

– ADC Linker

Pathway

– JAK/STAT signaling|||Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.