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Indophagolin

SKU T8946-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 85 CAD through 1,261 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Indophagolin is a potent, indoline-containing autophagy inhibitor with an IC50 of 140 nM, and it antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40, and 3.49 μM, respectively.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8946

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15BrClF3N2O3S

References

– Carnero Corrales MA, et al. Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin [published online ahead of print, 2021 Mar 9]. Cell Chem Biol. 2021;S2451-9456(21)00102-1.

CAS Number

– 1207660-00-1

Molecular Weight

– C19H15BrClF3N2O3S

Compound Purity

– 0.9976

SMILES

– FC(F)(F)c1cc(NS(=O)(=O)c2cc3N(CCc3cc2Br)C(=O)C2CC2)ccc1Cl

Pathway

– Membrane transporter/Ion channel|||Autophagy|||GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.