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IMR-1A

SKU T3540-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 70 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3540

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H11NO5S2

Citations

– 1. Tang Y, Song H, Wang Z, et al. Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations. Cell Reports. 2022, 39(2): 110622 2. Tang Y, Song H, Wang Z, et al.Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations.Cell Reports.2022, 39(2): 110622.

References

– Astudillo L,et al. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Cancer Res. 2016 Jun 15;76(12):3593-603.

CAS Number

– 331862-41-0

Molecular Weight

– C13H11NO5S2

Compound Purity

– 0.971

SMILES

– COc1cc(C=C2SC(=S)NC2=O)ccc1OCC(O)=O

Target

– Others

Pathway

– Metabolism|||Proteases/Proteasome|||Neuroscience|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.