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Ilorasertib

SKU TQ0059-1 mg Category Small Compound Brand: TargetMol

Price range: 53 CAD through 955 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TQ0059

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H21FN6O2S

References

– Gao C, et al. Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase. J Mol Model. 2015 Jul;21(7):167.

CAS Number

– 1227939-82-3

Molecular Weight

– C25H21FN6O2S

Compound Purity

– 0.9803

SMILES

– NC1=C2C(=C(C=N1)C3=CN(CCO)N=C3)SC=C2C4=CC=C(NC(NC5=CC(F)=CC=C5)=O)C=C4

Pathway

– Apoptosis|||Angiogenesis|||Cell Cycle/Checkpoint|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.