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Homoharringtonine
$70 – $383
Products Details
Product Description
– Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.
Web ID
– HY-14944
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H39NO9
References
– [1]Cao W, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015 Jul 13;5:8477
CAS Number
– 26833-87-4
Molecular Weight
– 545.62
Compound Purity
– 99.96
SMILES
– [H][C@@]12[C@](CCC3)(C=C(OC)[C@]2(OC([C@](CCCC(O)(C)C)(O)CC(OC)=O)=O)[H])N3CCC4=CC5=C(OCO5)C=C14
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 1.4 mg/mL (ultrasonic)
Target
– STAT
Isoform
– STAT3
Pathway
– JAK/STAT Signaling;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
