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Hispolon

$190$600

Products Details

Product Description

– Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities[1].

Web ID

– HY-150521

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C12H12O4

References

– [1]Sarfraz A, et al. Hispolon: A natural polyphenol and emerging cancer killer by multiple cellular signaling pathways. Environ Res. 2020 Nov;190:110017. |[2]Arcella A, et al. Effects of hispolon on glioblastoma cell growth. Environ Toxicol. 2017 Sep;32(9):2113-2123. |[3]Huang CY, et al. Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy. Nutrients. 2020 Jun 10;12(6):1742. |[4]Liao KF, et al. Hispolon Induces Apoptosis, Suppresses Migration and Invasion of Glioblastoma Cells and Inhibits GBM Xenograft Tumor Growth In Vivo. Molecules. 2021 Jul 26;26(15):4497.

CAS Number

– 173933-40-9

Molecular Weight

– 220.22

Compound Purity

– 99.67

SMILES

– CC(/C=C(O)/C=C/C1=CC(O)=C(C=C1)O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic;warming;heat to 70°C)

Target

– Antibiotic

Pathway

– Anti-infection

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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