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HIF-1 inhibitor-5

Products Details

Product Description

– HIF-1 inhibitor-5 (Compound 16e) is a potent HIF-1 inhibitor with an IC50 of 2.38 μM. HIF-1 inhibitor-5 possesses anti-angiogenic potential[1].

Web ID

– HY-149260

Shipping

– Room temperature

Molecular Formula

– C28H35NO5

References

– [1]Xu H, et al. Design, synthesis and evaluation of the novel chalcone derivatives with 2,2-dimethylbenzopyran as HIF-1 inhibitors that possess anti-angiogenic potential. Eur J Med Chem. 2023 Mar 15;250:115171.

Molecular Weight

– 465.58

SMILES

– O=C(C1=C(C2=C(OC(C)(C=C2)C)C=C1)O)/C=C/C3=CC(C(C=C3)OC)OCCCN4CCCC4

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– HIF/HIF Prolyl-Hydroxylase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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