Download Files:

HI5

SKU T73581-25 mg Category Small Compound Brand: TargetMol

Price range: 2,432 CAD through 4,000 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

Clear

Products Details

Product Description

– HI5, a potent inhibitor of tubulin and indoleamine 2,3-dioxygenase (IDO), exhibits an inhibitory concentration (IC50) of 70 nM in HeLa cells. It suppresses IDO expression, reduces kynurenine production, and enhances T cell activation and proliferation. Additionally, HI5 impedes tubulin polymerization and cell migration, induces G2/M phase arrest, and leads to apoptosis through the mitochondrial-dependent apoptosis pathway while generating reactive oxidative stress in HeLa cells, making it a valuable compound for anticancer research.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T73581

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C42H43N5O8

CAS Number

– 2411548-90-6

Molecular Weight

– C42H43N5O8

SMILES

– C(C(C(OCCC1=CN(CC2=CC(C(OC3=C(OC)C=CC(/C=CC4=CC(OC)=C(OC)C(OC)=C4)=C3)=O)=CC=C2)N=N1)=O)N)C=5C=6C(N(C)C5)=CC=CC6

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.