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HhAntag

SKU T3460-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 70 CAD through 1,728 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3460

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H23ClN4O3

Citations

– 1. Li H, Ou J, Li Y, et al. ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude. Communications Biology. 2022, 5(1): 1-13.

References

– Actis, Marcelo; Connelly, Michele C.; Mayasundari, Anand et al. A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription. Biopolymers (2011), 95(1), 24-30.

CAS Number

– 496794-70-8

Molecular Weight

– C24H23ClN4O3

Compound Purity

– 0.9573

SMILES

– COc1cc(OC)cc(c1)C(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(ccc2[nH]1)N(C)C

Pathway

– GPCR/G Protein|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.