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Products Details
Product Description
– HDAC6-IN-12 (compound GZ) is a potent HDAC6 inhibitor. HDAC6-IN-12 has anticancer activity through merges into DNA strands causing DNA damage. HDAC6-IN-12 can be used for cancer research[1].
Web ID
– HY-150722
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H39F2N3O5
References
– [1]Li Y, et, al. Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor. Bioorg Med Chem Lett. 2022 Sep 15;72:128881.
CAS Number
– 2803866-44-4
Molecular Weight
– 487.58
SMILES
– CCCCCCCCCCCCCCC(NC(C=CN1[C@@H]2O[C@H](CO)[C@H](C2(F)F)O)=NC1=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
