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Products Details
Product Description
– HDAC6/HSP90-IN-2 (compound 6e) is a dual inhibitor of HDAC6 and Hsp90, with IC50s of 105.7 and 61 nM, respectively. HDAC6/HSP90-IN-2 can be used for the research of cancer[1].
Web ID
– HY-150774
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H22N2O5
References
– [1]Chae HY, et al. Design, synthesis, and biological evalution of bifunctional inhibitors against Hsp90-HDAC6 interplay. Eur J Med Chem. 2022 Jul 6;240:114582.
CAS Number
– 2803866-22-8
Molecular Weight
– 358.39
SMILES
– OC1=C(C(C)C)C=C(C(N(C)CC2=CC=C(C=C2)C(NO)=O)=O)C(O)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HDAC;HSP
Isoform
– HDAC1;HDAC3;HDAC6;HDAC7
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
