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GW 542573X

SKU T22826-1 mg Category Small Compound Brand: TargetMol

Price range: 51 CAD through 1,355 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of hSK1 from an EC50 (Ca2+) value of 410 nM to 240 nM, which can be used to study neurological disorders.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T22826

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H28N2O5

References

– Hougaard C, et al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol Pharmacol. 2009;76(3):569-578.

CAS Number

– 660846-41-3

Molecular Weight

– C19H28N2O5

Compound Purity

– 0.9991

SMILES

– N(C(OCC1CCN(C(OC(C)(C)C)=O)CC1)=O)C2=C(OC)C=CC=C2

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.