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GsMTx4 TFA (1209500-46-8 free base)

SKU TP1300-1 mg Category Peptide Brand: TargetMol

Price range: 749 CAD through 3,440 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TP1300

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C187H279N48O48S6F3

Citations

– 1. Chen L, Yan Y, Kong F, et al. Contribution of Oxidative Stress Induced by Sonodynamic Therapy to the Calcium Homeostasis Imbalance Enhances Macrophage Infiltration in Glioma Cells. Cancers. 2022, 14(8): 2036 2. Piezo1 regulates colon stem cells to maintain epithelial homeostasis through SCD1-Wnt-β-catenin and programming fatty acid metabolism

References

– Gnanasambandam R, et al. GsMTx4: Mechanism of Inhibiting Mechanosensitive Ion Channels. Biophys J. 2017 Jan 10;112(1):31-45.

Molecular Weight

– C187H279N48O48S6F3

Compound Purity

– 0.9981

SMILES

– [H]NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CC(N)=O)C(N1CCC[C@H]1C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)CS)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)CS)=O)=O)=O)=O)=O)=O)CS)=O)CS)=O)=O)CC(O)=O)=O)CC(O)=O)=O)=O)=O)=O)CS)=O)=O)CC6=CNC7=C6C=CC=C7)=O)CC8=CNC9=C8C=CC=C9)=O)CC%10=CC=CC=C%10)=O)=O)=O)CS)=O.O=C(O)C(F)(F)F

Pathway

– Membrane transporter/Ion channel

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.