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GSK3395879

SKU T15439-25 mg Category Small Compound Brand: TargetMol

Price range: 3,392 CAD through 5,920 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– GSK3395879 is a selective, orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) with an IC50 of 1 nM for hTRPV4.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T15439

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H15F4N3O5S

References

– Brnardic EJ, et al. Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4). J Med Chem. 2018 Nov 8;61(21):9738-9755.

CAS Number

– 2215852-91-6

Molecular Weight

– C20H15F4N3O5S

SMILES

– O([C@@H]1[C@@](CO)(O)CN(S(=O)(=O)C2=C(C#N)C=C(C(F)(F)F)C=C2)C1)C3=CC(F)=C(C#N)C=C3

Target

– Others

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.