Download Files:

GSK1016790A

SKU T6848-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 50 CAD through 910 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6848

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H32Cl2N4O6S2

Citations

– 1. Zheng Q, Zou Y, Teng P, et al. Mechanosensitive Channel PIEZO1 Senses Shear Force to Induce KLF2/4 Expression via CaMKII/MEKK3/ERK5 Axis in Endothelial Cells. Cells. 2022, 11(14): 2191 2. Kong S, Chen T, Jia X, et al.Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity.Journal of Neuroinflammation.2023, 20(1): 1-22.

References

– Thorneloe KS, et al. J Pharmacol Exp Ther. 2008, 326(2):432-42.

CAS Number

– 942206-85-1

Molecular Weight

– C28H32Cl2N4O6S2

Compound Purity

– 0.9625

SMILES

– CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1Cl

Pathway

– Membrane transporter/Ion channel|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.