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GSK-843

Name: GSK-843 | RIP3 Inhibitor — Buy Online | Immunomart
Brand: TargetMol
SKU: T11474-1 mg
Price: 238 CAD
Availability: InStock

SKU T11474-1 mg Category Small Compound Brand: TargetMol

238 CAD

Only 1000 item(s) left in stock.

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– GSK-843 (GSK’843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase. It has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the SDH of CFA mice, and can be used as adjunctive [research relevance to related conditions].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11474

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15N5S2

References

– Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.

CAS Number

– 1601496-05-2

Molecular Weight

– C19H15N5S2

Compound Purity

– 0.9918

SMILES

– Cc1cc(-c2cnc(N)c3c(csc23)-c2ccc3scnc3c2)n(C)n1

Target

– Others

Pathway

– NF-κB|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.