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GS-441524

SKU T7222-25 mg Category Small Compound Brand: TargetMol

Price range: 54 CAD through 109 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7222

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H13N5O4

Citations

– 1. Wang Q, Wu J, Wang H, et al. Structural basis for RNA replication by the SARS-CoV-2 polymerase. Cell. 2020, 182(2): 417-428. e13. 2. Bennett R P, Postnikova E N, Eaton B P, et al. Sangivamycin is highly effective against SARS-CoV-2 in vitro and has favorable drug properties. JCI insight. 2022, 7(1). 3. Xu L, Tan B, Huang D, et al. Remdesivir inhibits renal fibrosis in obstructed kidneys. Frontiers in Pharmacology. 2021, 12: 1668 4. Xu L, Tan B, Huang D, et al. Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys. Frontiers in Pharmacology. 2021, 12: 1668. 5. Mohseni N, Royster A, Ren S, et al.A novel compound targets the feline infectious peritonitis virus nucleocapsid protein and inhibits viral replication in cell culture.Journal of Biological Chemistry.2023: 102976.

References

– Pedersen N C , Perron M , Bannasch M , et al. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis[J]. Journal of Feline Medicine & Surgery, 2019.

CAS Number

– 1191237-69-0

Molecular Weight

– C12H13N5O4

Compound Purity

– 0.9878

SMILES

– Nc1ncnn2c(ccc12)[C@@]1(O[C@H](CO)[C@@H](O)[C@H]1O)C#N

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.