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Products Details
Product Description
– GNE684 is a potent inhibitor of receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM for human, 189 nM for mouse, and 691 nM for rat RIP1, respectively [1].
Web ID
– T11442
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H24N6O3
References
– Patel S, et al. RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ. 2019 May 17.
CAS Number
– 2438637-64-8
Molecular Weight
– C23H24N6O3
SMILES
– C(N[C@@H]1C(=O)N(C)C=2C(CC1)=CC(OC)=NC2)(=O)C3=NN4[C@@H](CCC4=N3)C5=CC=CC=C5
Target
– Histone Demethylase
Pathway
– Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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