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Glutaminyl Cyclase Inhibitor 3

SKU T11422-25 mg Category Small Compound Brand: TargetMol

Price range: 3,152 CAD through 5,440 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Glutaminyl Cyclase Inhibitor 3, a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor (IC50: 4.5 nM). It significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11422

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H32N6O2S

References

– Hoang VH, et al. Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents Based on Rational Design. J Med Chem. 2017 Mar 23;60(6):2573-2590.

CAS Number

– 2092921-50-9

Molecular Weight

– C24H32N6O2S

SMILES

– O(C)C1=C(OCCCCC=2C=C(N)N=CC2)C=CC(NC(NCCCN3C(C)=CN=C3)=S)=C1

Target

– Others

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.