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GLPG2534
$340 – $2,800
Products Details
Product Description
– GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4. GLPG2534 can be used for the research of inflammatory skin diseases[1].
Web ID
– HY-153224
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C21H24N6O4
References
– [1]Lavazais S, et al. IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases. Sci Transl Med. 2023 Feb 15;15(683):eabj3289.
CAS Number
– 2095615-97-5
Molecular Weight
– 424.45
Compound Purity
– 98.05
SMILES
– N#CC(C=N1)=CC=C1N2C3=NC(NC4CCOCC4)=C(OCCOCCO)C=C3N=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– IRAK
Isoform
– IRAK1;IRAK4
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
