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Germacrone

SKU T2945-5 mg Category Natural Product Brand: TargetMol

Price range: 66 CAD through 336 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Germacrone is extracted from Curcuma zedoaria and has anti-inflammatory, anti-androgenic and antiviral activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2945

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H22O

Citations

– 1. Li Z, Wang Z, Dong F, et al. Germacrone Attenuates Hepatic Stellate Cells Activation and Liver Fibrosis via Regulating Multiple Signaling Pathways. Frontiers in Pharmacology. 2021: 2750. 2. Schepetkin, Igor A., et al. Chemical Composition and Immunomodulatory Activity of Essential Oils from Rhododendron albiflorum. Molecules. 26.12 (2021): 3652. 3. Kaduk J A, Gates-Rector S, Blanton T N. Crystal structure of a second polymorph of germacrone, C15H22O. Powder Diffraction. 2022: 1-7. 4. Wang Y, He X, Xue M, et al.Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.Free Radical Research.2023 (just-accepted): 1-36. 5. Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects

References

– Xie XH, et al. Germacrone reverses Adriamycin resistance through cell apoptosis in multidrug-resistant breast cancer cells. Exp Ther Med. 2014 Nov;8(5):1611-1615.

CAS Number

– 6902-91-6

Molecular Weight

– C15H22O

Compound Purity

– 0.9888

SMILES

– CC(C)=C1CC=C(C)/CCC=C(C)/CC1=O

Pathway

– Microbiology/Virology|||Immunology/Inflammation|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.