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GDC-0214

SKU T9826-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 142 CAD through 1,952 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T9826

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H28ClF2N9O3

References

– Braithwaite IE, et al. Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial. J Allergy Clin Immunol. 2021 Sep;148(3):783-789.

CAS Number

– 1831144-46-7

Molecular Weight

– C28H28ClF2N9O3

Compound Purity

– 0.9975

SMILES

– N(C(=O)C1=C2N(N=C1)C=CC=N2)C=3C(=NN(CC(=O)N4CCC(N(CCC#N)C)CC4)C3)C5=C(OC(F)F)C=CC(Cl)=C5

Pathway

– Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Angiogenesis|||JAK/STAT signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.