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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T3070
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H35N5
Citations
– 1. Zheng H T, Fu T, Zhang H Y, et al. Progesterone-regulated Hsd11b2 as a barrier to balance mouse uterine corticosterone. Journal of Endocrinology. 2020, 244(1): 177-187
2. Li B, Yan Y P, He Y Y, et al.IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice.Science Signaling.2023, 16(774): eadd0645.
3. Lei X, Li Z, Huang M, et al.Gli1-mediated tumor cell-derived bFGF promotes tumor angiogenesis and pericyte coverage in non-small cell lung cancer.Journal of Experimental & Clinical Cancer Research.2024, 43(1): 1-18.
References
– Lauth M, et al. Proc Natl Acad Sci, 2007, 104(20), 8455-8560
CAS Number
– 500579-04-4
Molecular Weight
– C27H35N5
Compound Purity
– 0.98
SMILES
– CN(C)c1ccccc1CN1CCCN(Cc2ccccc2N(C)C)C1c1ccncc1
Pathway
– GPCR/G Protein|||Autophagy|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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