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G5-7

SKU T8742-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 74 CAD through 1,197 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8742

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H19F2NO3

References

– Kunyan He, et al. Blockade of glioma proliferation through allosteric inhibition of JAK2. Sci Signal. 2013 Jul 9;6(283):ra55.

CAS Number

– 939681-36-4

Molecular Weight

– C22H19F2NO3

Compound Purity

– 0.9937

SMILES

– CCOC(=O)N1CC(=Cc2ccccc2F)C(=O)C(C1)=C/c1ccccc1F

Pathway

– JAK/STAT signaling|||Angiogenesis|||Chromatin/Epigenetic|||Apoptosis|||Stem Cells|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.