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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T7939
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H33NO2
Citations
– 1. Wang X, Li X, Wang J, et al. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. Journal of Cell Biology. 2022, 221(7): e202111125
2. Zhang T, Wang Y, Li Q, et al. Mesenchymal stromal cells equipped by IFNα empower T cells with potent anti-tumor immunity. Oncogene. 2022: 1-16.
3. Zhang J, Wang Z, Wei X, et al.The suppression of the SPHK1/S1P/S1PR3 signaling pathway diminishes EGFR activation and increases the sensitivity of non-small cell lung cancer to gefitinib.Current Research in Pharmacology and Drug Discovery.2025: 100212.
References
– Szepanowski, Fabian, Derksen, Angelika, Steiner, Irina,et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling[J]. Journal of Neuroinflammation, 13(1):143.
CAS Number
– 162359-55-9
Molecular Weight
– C19H33NO2
Compound Purity
– 0.996
SMILES
– CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
Pathway
– GPCR/G Protein|||Cytoskeletal Signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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