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Farudodstat

SKU T10384-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 69 CAD through 658 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity, showing potential as a first-in-class candidate in AML [Acute Myeloid Leukemia].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T10384

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H14F2N2O3

References

– Marco L. Lolli, et al. Human Dihydroorotate Dehydrogenase (hDHODH) as a new target on Acute Myelogenous Leukemia (AML): Targeting Myeloid Differentiation using Potent and Innovative hDHODH Inhibitors. 23rd Swedish Conference on Macromolecular Structure and Function Tällberg, 14-17 June 2019

CAS Number

– 1035688-66-4

Molecular Weight

– C19H14F2N2O3

Compound Purity

– 0.9836

SMILES

– COc1cccc(c1)-c1cc(F)c(Nc2ncccc2C(O)=O)c(F)c1

Target

– Others

Pathway

– Cell Cycle/Checkpoint|||Apoptosis|||DNA Damage/DNA Repair|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.