Download Files:

EZM0414

SKU T9969-1 mg Category Small Compound Brand: TargetMol

Price range: 446 CAD through 4,240 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– EZM0414 is a potent and selective, orally bioavailable inhibitor of SETD2 with an IC50 of 18 nM in biochemical assays and 34 nM in cellular assays, potentially useful for researching relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma [1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T9969

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H29FN4O2

References

– Jennifer Totman, et al. Pharmacologic Inhibition of the Histone Methyltransferase SETD2 with EZM0414 As a Novel Therapeutic Strategy in Relapsed or Refractory Multiple Myeloma and Diffuse Large B-cell Lymphoma.

CAS Number

– 2411748-50-8

Molecular Weight

– C22H29FN4O2

Compound Purity

– 0.9958

SMILES

– [H][C@@]1(CCC[C@H](C1)NC(=O)c1cc2c(F)ccc(C)c2[nH]1)N1CCN(CC1)C(C)=O

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.