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ER covalent antagonist-1
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– ER covalent antagonist-1 (Compound 39D) acts as an antagonist of the estrogen receptor α (ERα). This compound inhibits the proliferation of ERα-positive MCF-7 cells with an IC50 of 0.98 μM, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. Additionally, ER covalent antagonist-1 demonstrates antitumor activity in mouse models.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T204764
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C33H32N2O5S
CAS Number
– 2757498-74-9
Molecular Weight
– C33H32N2O5S
SMILES
– O(C1=C(C(=O)C2=CC=CC=C2)SC=3C1=CC=C(O)C3)C4=CC=C(OC5CN(C/C=C/C(=O)N6CCCCC6)C5)C=C4
Pathway
– Apoptosis|||Endocrinology/Hormones
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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