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EGFR-IN-99

SKU T35901-1 mg Category Small Compound Brand: TargetMol

Price range: 206 CAD through 4,528 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor with antiproliferative activity for the study of non-small cell lung cancer (NSCLC).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T35901

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H22FN7O3

References

– Jang J,et al. Discovery of a Highly Potent and Broadly Effective Epidermal Growth Factor Receptor and HER2 Exon 20 Insertion Mutant Inhibitor. Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11629-11633.

CAS Number

– 2068806-31-3

Molecular Weight

– C25H22FN7O3

Compound Purity

– 0.9775

SMILES

– O=C(C=C)NC1=CC=CC(=C1)N(C(=O)OCC2=CC=C(F)C=C2)C3=NC(=NC=C3)NC=4C=NN(C4)C

Pathway

– JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.