Download Files:

EGFR-IN-5

SKU T11160-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 171 CAD through 1,269 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg

Clear

Products Details

Product Description

– EGFR-IN-5 is a selective inhibitor of EGFR. The IC50s for EGFR, EGFR(L858R), EGFR(L858R/T790M), and EGFR(L858R/T790M/C797S) are 10.4, 1.1, 34, 7.2 nM, respectively.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T11160

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H38FN9O

References

– Zhang H, et al. Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. Eur J Med Chem. 2018 Mar 25;148:221-237.

CAS Number

– 2225887-26-1

Molecular Weight

– C31H38FN9O

Compound Purity

– 0.9817

SMILES

– N(C=1N=C(C2=C(N1)C=NC(NC3=CC=C(C=N3)N4CCC(N(C)C)CC4)=C2)N5CCC(CO)CC5)C6=CC=C(F)C=C6

Target

– Others

Pathway

– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.