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Eflornithine hydrochloride hydrate
48 CAD – 286 CADPrice range: 48 CAD through 286 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific and irreversible inhibitor of the ornithine decarboxylase (ODC). Eflornithine hydrochloride hydrate has antitumor activity and has also been used in the hirsutism Eflornithine hydrochloride hydrate has antitumor activity and is also used in the treatment of hirsutism.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T2593
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C6H15ClF2N2O3
Citations
– 1. Mastrodomenico V, Esin J J, Graham M L, et al. Polyamine depletion inhibits bunyavirus infection via generation of noninfectious interfering virions. Journal of Virology. 2019 May 1. pii: JVI.00530-19
2. Kicmal T M, Tate P M, Dial C N, et al. Polyamine depletion abrogates enterovirus cellular attachment. Journal of Virology. 2019, 93(20): e01054-19
3. Dial C N, Tate P M, Kicmal T M, et al. Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity. Viruses. 2019 Apr 30;11(5)
4. Firpo M R, LoMascolo N J, Petit M J, et al.Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection.PLoS pathogens.2023, 19(4): e1011317.
References
– Yoda H, et al. Plant Physiol. 2006, 142(1):193-206.
CAS Number
– 96020-91-6
Molecular Weight
– C6H15ClF2N2O3
Compound Purity
– 0.9945
SMILES
– O.Cl.NCCCC(N)(C(F)F)C(O)=O
Pathway
– Others|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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