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DS18561882
Price range: 187 CAD through 2,864 CAD
Products Details
Product Description
– DS18561882 is an orally available, selective and potent inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with antitumor activity, inhibits MTHFD1 activity and can be used in the study of breast cancer.
Web ID
– T11103
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H31F3N4O6S
References
– Kawai J, et al. Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with In Vivo Anti-Tumor Activity. J Med Chem. 2019 Oct 22.
CAS Number
– 2227149-22-4
Molecular Weight
– C28H31F3N4O6S
Compound Purity
– 0.9963
SMILES
– C[C@H]1CN(CCN1C)c1ccc2c3CCN(Cc3c(=O)oc2c1C)C(=O)c1ccc(NS(C)(=O)=O)c(OC(F)(F)F)c1
Target
– ADC Linker
Pathway
– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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