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DKFZ-748
$250 – $1,980
Products Details
Product Description
– DKFZ-748 is a selective HDAC10 inhibitor (pIC50=7.66), and shows anti-tumor activity[1].
Web ID
– HY-151590
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H23N3O3
References
– [1]Steimbach RR, et al. Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J Am Chem Soc. 2022 Oct 19;144(41):18861-18875.
CAS Number
– 2490709-68-5
Molecular Weight
– 329.39
Compound Purity
– 98.0
SMILES
– O=C(NCCN(CCCC(NO)=O)C)C1=C2C=CC=CC2=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
